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Histology 

TISSUES:

Connective Tissues

connective tissues

*source unknown

I). Definition

1). binding

2). support

 3). binding

4). insulation

 5). transportation.

 

II). Classes of Connective Tissue

1). connective tissue proper

2). cartilage

3). bone

4). blood

 

III). Characteristics of Connective Tissues

A). Not adjacent to other cells

B). Extra Cellular Matrix

C). Common origin in embryonic development.

D). Vary in degrees of vascularity

E). Vary in degrees of regeneration

F).  Vary in degrees of innervation

 

IV). Elements of connective tissues.

Connective tissues

A). Ground substance

B). Cells

1). Type specific immature (stem) cells

2). Fixed cells:

Fibroblasts:

Mast cells:

3). Wandering cells:

Macrophages:

C). Fibers: supply support.

1). Collagenous Fibers

collagen fiber

http://www.ouhsc.edu/histology/text%20sections/connective%20tissue.html

2). Elastic Fibers

elastic fiber

http://coffeeblackandcigarettes.wordpress.com/2007/01/ 

3). Reticular Fibers

reticular fibers

http://faculty.une.edu/com/abell/histo/Histolab4b.htm

V). Types of Connective Tissue

 A). Connective Tissue Proper

1).  Loose Connective Tissue

i). Areolar Connective Tissue

Matrix with fibroblasts supported by gel membrane with collagenous & elastic fibers

ii). Adipose Tissue (fat)

Tightly packed & highly vascularized

An oil droplet pushes the nucleus to one side

iii). Reticular Connective Tissue

Thin collagenous fibers that form a 3-dimensional network

areolar tissue

adipose tissues

reticular connective tissue

Areolar Connective Tissue

Adipose Tissue

Reticular Connective Tissue

LABEL:

bullet

fibroblast cell

bullet

elastic fibers

bullet

collagen fibers

LABEL:

bullet

fat storage area

bullet

nucleus

LABEL

bullet

white blood cells

bullet

reticular (collagen) fibers

http://faculty.clintoncc.suny.edu/faculty/michael.gregory

http://home.mc.ntu.edu.tw/~histol/Ffolder_

        2). Dense Connective Tissues

               i). Regular Dense Connective Tissue

Collagen runs parallel to the direction of pull. Strong white flexible structures.

Poor blood supply, slow tissue repair

               ii). Irregular Dense Tissue

Fibers interwoven in different directions to pull in different directions

               iii). Elastic Connective Tissue

Branched bundles of elastic fibers that run parallel.

 

regular dense

Regular Dense Connective Tissue

Irregular Dense Tissue

Elastic Connective Tissue

LABEL

bullet

fibroblast cell

bullet

collagen fibers

 

LABEL

bullet

elastic fibers

bullet

collagen fibers

http://io.uwinnipeg.ca/~simmons/

http://www.pathguy.com/histo/052.htm

http://faculty.une.edu/com/abell/histo/Histo

B). Cartilage

Rigid supports, frameworks, and attachment

 

Withstands both tension and compression and it is avascular (few blood vessels) and lacks nerve fibers.

1). Hyaline Cartilage

fine collagen fibers give tissue a “washed out” appearance

Chondroblasts  are found in large lacuna.  

2). Elastic Cartilage

Elastic cartilage has visible elastic fibers

3). Fibrocartilage

Visible collagen fibers

Small lacuna

Where strong support is needed.

hyaline cartilage

elastic cartilage

fibrocartilage

Hyaline Cartilage

Elastic Cartilage

Fibrocartilage

LABEL

bullet

lacuna

bullet

chondrocyte cell

bullet

extracellular matrix

LABEL

bullet

lacuna

bullet

chondrocyte cell

bullet

elastic fibers

bullet

extracellular matrix

LABEL

bullet

lacuna

bullet

chondrocyte cell

bullet

collagen fibers

http://kentsimmons.uwinnipeg.ca/cm1504/

http://faculty.une.edu/com/abell/histo/

http://biology.clc.uc.edu/fankhauser/

C). Bone

Bone is very rigid because in addition to collagen fibers it has a dense matrix of calcium salts.

The matrix forms a circular pattern

bone histology

Bone

LABEL

bullet

osteon

bullet

central canal

http://www.siumed.edu/~dking2/ssb/NM036b.htm

D). Blood

Blood consists of blood cells surrounded by a nonliving matrix of plasma made up of soluble protein fibers

blood

 Blood

LABEL

bullet

extracellular matrix

bullet

red blood cell

http://www.medicalhistology.us/twiki/bin/view/Main/