APII Histology Home Page

Blood Cells

Blood smear

blood smeear

http://www.visualsunlimited.com/browse/vu442/

http://pathy.med.nagoya-u.ac.jp/atlas/doc/node1.html

Erythrocytes

(red blood cells; RBCs)

Blood smears containing some platelets. Erythrocytes carry oxygen. The RBCs appear hollow because mature RBCs have no nuclei. The cells are not hollow just thinner in the center.

blood smear

Red blood cells

http://medinfo.ufl.edu/year1/histo/images/

http://www.spelman.edu/~biology/bio112/lab/lab7.html

Erythrocytes

Iron in the hemoglobin is responsible for the red appearance. When oxygen combines with the iron to form oxyhemoglobin it turns red. When the oxygen is removed there is a purplish or bluish tinge.

red blood cells Human blood smear

Erythrocytes

 

http://a-s.clayton.edu/biology/biol1151L/lab03/

Blood smear

Containing erythrocytes, lymphocytes and platelets.

http://www.fed.cuhk.edu.hk/~johnson/photomicrographs/

Red blood cells blood cells

Red Blood Cells as seen with an

electron microscope

http://whyfiles.org/090doping_sport/3.html

Red Blood Cells, Platelets (purple) Leukocytes (orange and green) under an electron microscope

http://www.phoenix5.org/glossary/white_blood_cells.html

Platelets Platlets
http://science.nhmccd.edu/biol/cardio/blood.htm http://www2.uerj.br/~micron/atlas/atlasenglish/Blood/l

Platelets and Erythrocytes

Platelets are small cellular pieces that function to promote blood clotting. They adhere to a damaged region of a blood vessel and initiate a complex reaction. They have no nucleus.

They stain red to purple and are much smaller than red blood cells.

basophil basophil
http://science.nhmccd.edu/biol/cardio/blood.htm http://cellbio.utmb.edu/microanatomy/blood/

Basophil

(granular leukocytes)

Basophil with some platelets on the left. Basophils function as mast cells and can be identified from the other granulocyte (Eosinophils) by the differences in the structure of the nucleus. The nucleus of eosinopils is lobe whereas in the nucleus in basophils are not as notably lobulated. Less than 1% of leukocytes are basophils.

eosinophil eosinophil
http://pathmicro.med.sc.edu/ghaffar/innate.htm http://science.nhmccd.edu/biol/cardio/blood.htm

Eosinophils

(granular leukocyte)

Eosinophils are identified by bilobed nucleus and granular cytoplasm. About 2% to 4% of all leukocytes are eosinophils. Eosinophils are phagocytic cells with an affinity for antigen-antibody complexes.

neutrophil
http://science.nhmccd.edu/biol/cardio/blood.htm http://www.mcl.tulane.edu/classware/pathology/l

Neutrophils

(granular leukocytes)

Granules are very difficult to see. Neutrophils are identified by their nucleus that is made up of a number of lobes held together by strings of chromatin. Approximately 60% to 70% of all leukocytes are neutrophils. Neutrophils are phagocytic cells. They are particularly attracted to microorganisms.

monocyte

 

Monocyte
http://www.anatomy.dal.ca/Human_Histology/Lab7/ http://science.nhmccd.edu/biol/cardio/blood.htm

Monocytes

(agranular leukocyte)

Monocytes can be identified by the large horseshoe shaped nucleus. Approximately 3% to 8% of all leukocytes are monocytes. Monocytes function as phagocytes at the site of infection that destroy bacteria, foreign matter and cellular debris.

lymphocyte lymphocyte
http://altmed.creighton.edu/pelvic2/blyphocytes.htm http://science.nhmccd.edu/biol/cardio/blood.htm

Lymphocyte

(agranular leukocyte)

Both large and small lymphocytes contain a large dark nucleus that occupies most of the cytoplasm. 20% to 30% of all leukocytes are lymphocytes. Lymphocytes differentiate into plasma cells that produce antibodies.

lymphocyte atypical lymphocyte

Lymphocyte

(agranular leukocyte)

Both large and small lymphocytes contain a large dark nucleus that occupies most of the cytoplasm. 20% to 30% of all leukocytes are lymphocytes. Lymphocytes differentiate into plasma cells that produce antibodies.

http://www.bioltrop.org/14-techhemato

Atypical lymphocytes

Not spherical in shape indicating a disease condition

 

 

 

http://pathy.med.nagoya-u.ac.jp/atlas/doc/node10.html

leukemia leukemia
http://www.stanford.edu/group/cleary/research.html http://www.meds.com/leukemia/guide/guide_chapter4

Leukemia

Blood smear showing a large number of atypical leukocytes that indicates leukemia.

red blood cell under viral attack sickle cell anemia

Red Blood Cell under viral attack viewed under an electron microscope.

 

http://www.petech.ac.za/aids/2001HIVTheMost

Sickle Cell Anemia

Many of the erythrocytes are sickled shaped because of a missing amino acid in the hemoglobin chain.

http://sac.edu/HomePages/nigro_dan/biology_lab_

 

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