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Lymphatic System

Lymphatic System

I). General Function

A). Fluid Balance

B). Fat Absorption

C). Defense

II). Lymphatic Vessels and the Cardiac System

A). Associated with cardiovascular system

Lymphatic vessels

B).  There is no pump and lymphatic pressure is very low.

C). One way system

D). Lymph is moved by:

Direction of Lymphatic System

III). Structure of the Lymphatic Vessels

A). Lymphatic Capillaries

1).  blind-ended’ lymphatic capillaries found between the interstitial tissues and the cardiovascular system

2).  Lymphatic capillaries are

i.  Not found in the bones, teeth, and central nervous system. 

ii).  Very permeable

 
3).  Specialized capillaries called “lacteals” drain fat from the intestine in fatty lymph called “chyle

B). Lymphatic Collecting Vessels

 1).  Three distinct tunics

bullet tunica interna
bullet tunica media
bullet tunica externa

2).  Valves to prevent backflow.

Lymphatic vessels


C). Lymphatic Trunks

1). Intestinal Trunk

 

2). Lumbar Trunk

 

3). Bronchmediastinal Trunk

 

4). Subclavian Trunk

 

5). Jugular Trunks

 

Lymphatic System
 

D). Lymphatic Ducts

 

 

Major ducts:

1). Thoracic duct:

 

2). Right lymphatic duct

 

Cisterna chyli:  

An enlarged abdominal sac

 

 

IV). Lymphoid Cells

A). Macrophages (monocytes)

B). Lymphocytes:

Antigen: 
 
 
Antibody: 
 

Types of Lymphocytes

i). T lymphocytes (T cells)

Acts directly against virus infected cells and tumor cells.

ii). B lymphocytes (B cells)

 Produces antibodies (immunoglobulins)

C). Dendritic cells:

D). Reticular cells:

The lymphoid organs are encapsulated collections of diffuse lymphatic tissue that is made up of reticular connective tissue.

 

 

 

V). Lymphatic Follicles

Lympatic follicle

http://www.pathology.vcu.edu/education/lymph/lab1.a.html

 

A). Lymphatic follicles or nodules

B). Germinal centers (that stain lighter)

C). Aggregates of Lymphatic Follicles

Peyer's Patch

http://www.teaching-biomed.man.ac.uk/histology/T220.HTML

 

1). Peyer’s patches

2). Mucosa-Associated Lymphatic Tissues

3). Appendix

 

VI). Lymphoid Organs

A). Lymph Nodes

 

1). Location:

i.  cervical nodes

ii. axillary nodes

iii. inguinal nodes

iv. pelvic nodes

v. abdominal nodes

vi. thoracic nodes

vii supratonchlear nodes

Lymph nodes

2). Function:

i). Filter the lymph.

ii). Activate the immune system.

 

3). Structure of Lymph Nodes

Lymph node Lymph Node

i). Capsule

ii). Regions:

a). Cortex:

compartments with lymphatic follicles or nodules with germinal centers

b) Medulla:

 

iii). Afferent lymphatic vessels

iv). Efferent lymphatic vessels

 

B). Spleen

Spleen

1). Location

2). Functions

i). salvages the breakdown products of red blood cells

ii). Stores platelets

iii).  lymphocyte proliferation

3). Structure

i). Blood vessels

  • splenic artery
  •  splenic vein

ii). Regions

White Pulp

 

Red Pulp

Spleen Histology

                                             http://www.siumed.edu/~dking2/crr/CR036b.htm

C). Thymus

Thymus gland Thymus histology

1). Location

2). Function

3). Structure (histology)

i).  thymic lobules

  • Cortex
  • Medulla

ii).   Hassall’s corpuscles

 

 

D). Tonsils

Tonsils tonsils
http://home.hawaii.rr.com/dochazenfield/Tonsillectomy.htm

 

http://www.healthopedia.com/pictures/palatine-tonsil.html

 

 
1. Pharyngeal Tonsil
2. Palatine Tonsil
3. Lingual Tonsil

4. Epiglottis

1). Location

2). Named by location

i). Palatine tonsils

ii). Lingual tonsils

iii). Pharyngeal tonsils

iv). Tubal tonsils

3). Structures (histology)

Not completely encapsulated with blind end structures that are called crypts that trap bacteria.

Tonsil Histology Tonsil histology
http://www.cytochemistry.net/microanatomy/immune_system/lymphoid_tissues.htm http://asb.aecom.yu.edu/histology/labs/lab11_12/lab11_12.asp